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Coordination of DNA–PK Activation and Nuclease Processing of DNA Termini in NHEJ
DNA double-strand breaks (DSB), particularly those induced by ionizing radiation (IR), are complex lesions that can be cytotoxic if not properly repaired. IR-induced DSB often have DNA termini modifications, including thymine glycols, ring fragmentation, 3′-phosphoglycolates, 5′-hydroxyl groups, and...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096510/ https://ncbi.nlm.nih.gov/pubmed/20698792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3368 |
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