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IL-2(high) tissue-resident T cells in the human liver: Sentinels for hepatotropic infection

The liver provides a tolerogenic immune niche exploited by several highly prevalent pathogens as well as by primary and metastatic tumors. We have sampled healthy and hepatitis B virus (HBV)–infected human livers to probe for a subset of T cells specialized to overcome local constraints and mediate...

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Pubblicato in:J Exp Med
Autori principali: Pallett, Laura J., Davies, Jessica, Colbeck, Emily J., Robertson, Francis, Hansi, Navjyot, Easom, Nicholas J.W., Burton, Alice R., Stegmann, Kerstin A., Schurich, Anna, Swadling, Leo, Gill, Upkar S., Male, Victoria, Luong, TuVinh, Gander, Amir, Davidson, Brian R., Kennedy, Patrick T.F., Maini, Mala K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461007/
https://ncbi.nlm.nih.gov/pubmed/28526759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162115
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