Degradation Paradigm of the Gut Hormone, Pancreatic Polypeptide, by Hepatic and Renal Peptidases

Pancreatic polypeptide (PP) is a gut hormone that acts on Y4 receptors to reduce appetite. Obese humans display a reduced postprandial increase in PP and remain fully sensitive to the anorectic effects of exogenous PP. The utility of PP as an anti-obesity treatment is limited by its short circulatin...

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Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Cuenco, Joyceline, Minnion, James, Tan, Tricia, Scott, Rebecca, Germain, Natacha, Ling, Yiin, Chen, Rong, Ghatei, Mohammad, Bloom, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460925/
https://ncbi.nlm.nih.gov/pubmed/28323997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1827
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