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Pharmacokinetics, adverse effects and tolerability of a novel analogue of human pancreatic polypeptide, PP 1420

AIMS: The objectives of this phase 1 study were to confirm the tolerability of single ascending subcutaneous doses of PP 1420 in healthy subjects, to assess its adverse effects and to investigate the drug's pharmacokinetics and dose proportionality. METHODS: This was a double-blind, placebo-con...

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Detalhes bibliográficos
Main Authors: Tan, Tricia M, Field, Benjamin C T, Minnion, James S, Cuenco-Shillito, Joyceline, Chambers, Edward S, Zac-Varghese, Sagen, Brindley, Charlie J, Mt-Isa, Shahrul, Fiorentino, Francesca, Ashby, Deborah, Ward, Ian, Ghatei, Mohammad A, Bloom, Stephen R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269582/
https://ncbi.nlm.nih.gov/pubmed/21834938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04082.x
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