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Protein charge distribution in proteomes and its impact on translation

As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides may be important factors that affect protein express...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Requião, Rodrigo D., Fernandes, Luiza, de Souza, Henrique José Araujo, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460897/
https://ncbi.nlm.nih.gov/pubmed/28531225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005549
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