Protein charge distribution in proteomes and its impact on translation

As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides may be important factors that affect protein express...

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Publicado en:PLoS Comput Biol
Autores principales: Requião, Rodrigo D., Fernandes, Luiza, de Souza, Henrique José Araujo, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460897/
https://ncbi.nlm.nih.gov/pubmed/28531225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005549
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