Protein charge distribution in proteomes and its impact on translation

As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides may be important factors that affect protein express...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Requião, Rodrigo D., Fernandes, Luiza, de Souza, Henrique José Araujo, Rossetto, Silvana, Domitrovic, Tatiana, Palhano, Fernando L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460897/
https://ncbi.nlm.nih.gov/pubmed/28531225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005549
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