TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice

Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene cause central hypothyroidism. IGSF1 is a transmembrane glycoprotein of unknown function expressed in thyrotropin (TSH)-producing thyrotrope cells of the anterior pituitary gland. The protein is cotranslation...

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Publicado en:Endocrinology
Autores principales: Turgeon, Marc-Olivier, Silander, Tanya L., Doycheva, Denica, Liao, Xiao-Hui, Rigden, Marc, Ongaro, Luisina, Zhou, Xiang, Joustra, Sjoerd D., Wit, Jan M., Wade, Mike G., Heuer, Heike, Refetoff, Samuel, Bernard, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460797/
https://ncbi.nlm.nih.gov/pubmed/28324000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1788
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