IGSF1 Does Not Regulate Spermatogenesis or Modify FSH Synthesis in Response to Inhibins or Activins

Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene result in central hypothyroidism, often associated with macroorchidism. Testicular enlargement in these patients might be caused by increases in follicle-stimulating hormone (FSH) levels, as IGSF1 has been p...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Brûlé, Emilie, Heinen, Charlotte A, Smith, Courtney L, Schang, Gauthier, Li, Yining, Zhou, Xiang, Wang, Ying, Joustra, Sjoerd D, Wit, Jan M, Fliers, Eric, Repping, Sjoerd, van Trotsenburg, A S Paul, Bernard, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986638/
https://ncbi.nlm.nih.gov/pubmed/33796801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab023
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