11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome

CONTEXT: Androgen excess is a defining feature of polycystic ovary syndrome (PCOS), but the exact origin of hyperandrogenemia remains a matter of debate. Recent studies have highlighted the importance of the 11-oxygenated C19 steroid pathway to androgen metabolism in humans. In this study, we analyz...

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發表在:J Clin Endocrinol Metab
Main Authors: O’Reilly, Michael W., Kempegowda, Punith, Jenkinson, Carl, Taylor, Angela E., Quanson, Jonathan L., Storbeck, Karl-Heinz, Arlt, Wiebke
格式: Artigo
語言:Inglês
出版: Endocrine Society 2016
主題:
Clinical Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460696/
https://ncbi.nlm.nih.gov/pubmed/27901631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3285
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