11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome

CONTEXT: Androgen excess is a defining feature of polycystic ovary syndrome (PCOS), but the exact origin of hyperandrogenemia remains a matter of debate. Recent studies have highlighted the importance of the 11-oxygenated C19 steroid pathway to androgen metabolism in humans. In this study, we analyz...

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Publicado en:J Clin Endocrinol Metab
Autores principales: O’Reilly, Michael W., Kempegowda, Punith, Jenkinson, Carl, Taylor, Angela E., Quanson, Jonathan L., Storbeck, Karl-Heinz, Arlt, Wiebke
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2016
Materias:
Clinical Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460696/
https://ncbi.nlm.nih.gov/pubmed/27901631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3285
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