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Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Obesity-related albuminuria is associated with decline of kidney function and is considered a first sign of diabetic nephropathy. Suggested factors linking obesity to kidney dysfunction include low-grade inflammation, insulin resistance and adipokine dysregulation. Here, we investigated the effects...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Morrison, Martine C., Yakala, Gopala K., Liang, Wen, Wielinga, Peter Y., Salic, Kanita, van Koppen, Arianne, Tomar, Tushar, Kleemann, Robert, Heeringa, Peter, Kooistra, Teake
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460286/
https://ncbi.nlm.nih.gov/pubmed/28588299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02444-2
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