Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice

We previously showed that Irisin, a myokine released from skeletal muscle after physical exercise, plays a central role in the control of bone mass. Here we report that treatment with recombinant Irisin prevented bone loss in hind-limb suspended mice when administered during suspension (preventive p...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Colaianni, Graziana, Mongelli, Teresa, Cuscito, Concetta, Pignataro, Paolo, Lippo, Luciana, Spiro, Giovanna, Notarnicola, Angela, Severi, Ilenia, Passeri, Giovanni, Mori, Giorgio, Brunetti, Giacomina, Moretti, Biagio, Tarantino, Umberto, Colucci, Silvia C., Reseland, Janne E., Vettor, Roberto, Cinti, Saverio, Grano, Maria
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460172/
https://ncbi.nlm.nih.gov/pubmed/28588307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02557-8
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