The myokine irisin increases cortical bone mass

It is unclear how physical activity stimulates new bone synthesis. We explored whether irisin, a newly discovered myokine released upon physical activity, displays anabolic actions on the skeleton. Young male mice were injected with vehicle or recombinant irisin (r-irisin) at a low cumulative weekly...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Colaianni, Graziana, Cuscito, Concetta, Mongelli, Teresa, Pignataro, Paolo, Buccoliero, Cinzia, Liu, Peng, Lu, Ping, Sartini, Loris, Di Comite, Mariasevera, Mori, Giorgio, Di Benedetto, Adriana, Brunetti, Giacomina, Yuen, Tony, Sun, Li, Reseland, Janne E., Colucci, Silvia, New, Maria I., Zaidi, Mone, Cinti, Saverio, Grano, Maria
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593131/
https://ncbi.nlm.nih.gov/pubmed/26374841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516622112
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