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Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition

Candida albicans is an opportunistic fungal pathogen colonizing the oral cavity. C. albicans secreted aspartic protease Sap6 is important for virulence during oral candidiasis since it degrades host tissues to release nutrients and essential transition metals. We found that zinc specifically increas...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Kumar, Rohitashw, Breindel, Christine, Saraswat, Darpan, Cullen, Paul J., Edgerton, Mira
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460171/
https://ncbi.nlm.nih.gov/pubmed/28588252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03082-4
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