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Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition

Candida albicans is an opportunistic fungal pathogen colonizing the oral cavity. C. albicans secreted aspartic protease Sap6 is important for virulence during oral candidiasis since it degrades host tissues to release nutrients and essential transition metals. We found that zinc specifically increas...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kumar, Rohitashw, Breindel, Christine, Saraswat, Darpan, Cullen, Paul J., Edgerton, Mira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460171/
https://ncbi.nlm.nih.gov/pubmed/28588252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03082-4
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