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HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells
Immune responses primed by endogenous heat shock proteins, specifically gp96, can be varied, and mechanisms controlling these responses have not been defined. Immunization with low doses of gp96 primes T helper type 1 (Th1) immune responses, whereas high-dose immunization primes responses characteri...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460028/ https://ncbi.nlm.nih.gov/pubmed/28561043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15648 |
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