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Antigen-specific CD4(+) T cells drive airway smooth muscle remodeling in experimental asthma

Airway smooth muscle (ASM) growth contributes to the mechanism of airway hyperresponsiveness in asthma. Here we demonstrate that CD4(+) T cells, central to chronic airway inflammation, drive ASM remodeling in experimental asthma. Adoptive transfer of CD4(+) T cells from sensitized rats induced an in...

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Autores principales: Ramos-Barbón, David, Presley, John F., Hamid, Qutayba A., Fixman, Elizabeth D., Martin, James G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088014/
https://ncbi.nlm.nih.gov/pubmed/15902312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI19711
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