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Engineered clearing agents for the selective depletion of antigen-specific antibodies
Here we have designed a novel class of engineered antibody-based reagents (‘Seldegs') that induce the selective degradation of antigen-specific antibodies. We demonstrate the rapid and specific clearance of antibodies recognizing the autoantigen, myelin oligodendrocyte glycoprotein and tumour t...
Gardado en:
| Publicado en: | Nat Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460014/ https://ncbi.nlm.nih.gov/pubmed/28561044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15314 |
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