JunB is essential for IL-23-dependent pathogenicity of Th17 cells

CD4(+) T-helper cells producing interleukin-17 (IL-17), known as T-helper 17 (T(H)17) cells, comprise heterogeneous subsets that exhibit distinct pathogenicity. Although pathogenic and non-pathogenic T(H)17 subsets share a common RORγt-dependent T(H)17 transcriptional programme, transcriptional regu...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Hasan, Zafrul, Koizumi, Shin-ichi, Sasaki, Daiki, Yamada, Hayato, Arakaki, Nana, Fujihara, Yoshitaka, Okitsu, Shiho, Shirahata, Hiroki, Ishikawa, Hiroki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460000/
https://ncbi.nlm.nih.gov/pubmed/28555647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15628
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