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Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

The structure and function of spines and excitatory synapses are under the dynamic control of multiple signalling networks. Although tyrosine phosphorylation is involved, its regulation and importance are not well understood. Here we study the role of Pyk2, a non-receptor calcium-dependent protein-t...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Giralt, Albert, Brito, Veronica, Chevy, Quentin, Simonnet, Clémence, Otsu, Yo, Cifuentes-Díaz, Carmen, de Pins, Benoit, Coura, Renata, Alberch, Jordi, Ginés, Sílvia, Poncer, Jean-Christophe, Girault, Jean-Antoine
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459995/
https://ncbi.nlm.nih.gov/pubmed/28555636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15592
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