Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

The structure and function of spines and excitatory synapses are under the dynamic control of multiple signalling networks. Although tyrosine phosphorylation is involved, its regulation and importance are not well understood. Here we study the role of Pyk2, a non-receptor calcium-dependent protein-t...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Giralt, Albert, Brito, Veronica, Chevy, Quentin, Simonnet, Clémence, Otsu, Yo, Cifuentes-Díaz, Carmen, de Pins, Benoit, Coura, Renata, Alberch, Jordi, Ginés, Sílvia, Poncer, Jean-Christophe, Girault, Jean-Antoine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459995/
https://ncbi.nlm.nih.gov/pubmed/28555636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15592
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