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X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction
Current enzymatic systems for quantifying glycated hemoglobin are based on the FAD-containing enzyme fructosyl peptide oxidase (FPOX). FPOX has substrate specificity for fructosyl-(α) N-valyl-histidine derived from proteolytic digestion of the N-terminus of the HbA1c β-chain. This study reports the...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5459902/ https://ncbi.nlm.nih.gov/pubmed/28584265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02657-5 |
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