On the Oxygen Reactivity of Flavoprotein Oxidases: AN OXYGEN ACCESS TUNNEL AND GATE IN BREVIBACTERIUM STEROLICUM CHOLESTEROL OXIDASE

The flavoprotein cholesterol oxidase from Brevibacterium sterolicum (BCO) possesses a narrow channel that links the active center containing the flavin to the outside solvent. This channel has been proposed to serve for the access of dioxygen; it contains at its “bottom” a Glu-Arg pair (Glu-475—Arg-...

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Detalhes bibliográficos
Main Authors: Piubelli, Luciano, Pedotti, Mattia, Molla, Gianluca, Feindler-Boeckh, Susanne, Ghisla, Sandro, Pilone, Mirella S., Pollegioni, Loredano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259834/
https://ncbi.nlm.nih.gov/pubmed/18614534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802321200
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