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Whole Blood Profiling of Bacillus Calmette–Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation

Vaccination of infants with bacillus Calmette–Guérin (BCG) activates both the innate and adaptive arms of the immune response. The antimycobacterial effects of these responses most likely account for the ability of BCG to protect against childhood forms of tuberculosis (TB). There is also evidence f...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Smith, Steven G., Kleinnijenhuis, Johanneke, Netea, Mihai G., Dockrell, Hazel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459878/
https://ncbi.nlm.nih.gov/pubmed/28634479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00644
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