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Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation

The circulating concentrations of adiponectin, an antidiabetic adipokine, have been shown to be reduced in obesity, in relation to an increase in inflammation. The aim of the present work was to assess the effect of leptin replacement on adiponectin levels and expression as well as on markers of oxi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Frühbeck, Gema, Catalán, Victoria, Rodríguez, Amaia, Ramírez, Beatriz, Becerril, Sara, Portincasa, Piero, Gómez-Ambrosi, Javier
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459809/
https://ncbi.nlm.nih.gov/pubmed/28584304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02848-0
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