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Both cladribine and alemtuzumab may effect MS via B-cell depletion

OBJECTIVE: To understand the efficacy of cladribine (CLAD) treatment in MS through analysis of lymphocyte subsets collected, but not reported, in the pivotal phase III trials of cladribine and alemtuzumab induction therapies. METHODS: The regulatory submissions of the CLAD Tablets Treating Multiple...

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Detalhes bibliográficos
Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Baker, David, Herrod, Samuel S., Alvarez-Gonzalez, Cesar, Zalewski, Lukasz, Albor, Christo, Schmierer, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459792/
https://ncbi.nlm.nih.gov/pubmed/28626781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000360
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