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Alemtuzumab depletion failure can occur in multiple sclerosis

Alemtuzumab is a lymphocyte‐depleting antibody and one of the most effective treatments for relapsing multiple sclerosis. However, it also causes loss of immune‐tolerance leading to secondary autoimmunity and marked anti‐drug antibody responses. Although these anti‐drug responses have been reported...

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Détails bibliographiques
Publié dans:Immunology
Auteurs principaux: Dubuisson, Nicolas, Baker, David, Kang, Angray S., Pryce, Gareth, Marta, Monica, Visser, Leo H., Hofmann, Werner E., Gnanapavan, Sharmilee, Giovannoni, Gavin, Schmierer, Klaus
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980120/
https://ncbi.nlm.nih.gov/pubmed/29247512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12879
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