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Inactivation of sortilin (a novel lysosomal sorting receptor) by dominant negative competition and RNA interference

To assess the role of sortilin in the sorting and trafficking of sphingolipid activator proteins (SAPs) the function of sortilin was abolished by a dominant-negative mutant and by the use of RNAi. Mutant sortilin lacking the carboxyl-terminal region that contains the sorting signal abolished the tra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lefrancois, Stephane, Canuel, Maryssa, Zeng, Jibin, Morales, Carlos R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biological Procedures Online 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC545973/
https://ncbi.nlm.nih.gov/pubmed/15682222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1251/bpo101
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