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The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition

Antibodies are critical components of the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding surfaces. Nevertheless, most antibodies have similar architectures, with the variable immunoglobulin domains of the heavy and light chain each providing three hype...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Hsieh, Fu-Lien, Higgins, Matthew K
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459573/
https://ncbi.nlm.nih.gov/pubmed/28527239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27311
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