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Simultaneous localization of cosmids and chromosome R-banding by fluorescence microscopy: application to regional mapping of human chromosome 11.

A technique for nonradioactive in situ hybridization on human metaphase chromosomes has been developed to localize human cosmid clones. The simple procedure using two fluorescent dyes (fluorescein and propidium iodide) allows the simultaneous identification of chromosomal R-bands and hybridization s...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Cherif, D, Julier, C, Delattre, O, Derré, J, Lathrop, G M, Berger, R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2395867/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.17.6639
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