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Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes.

We report that ligation-mediated PCR (LMPCR) can be used for high-resolution study of metaphase chromosomes, and we discuss the role of metaphase chromatin structure in the preservation of differentiated cell states. The X chromosome-linked human PGK1 (phosphoglycerate kinase 1) promoter region was...

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Detaylı Bibliyografya
Asıl Yazarlar: Hershkovitz, M, Riggs, A D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC42487/
https://ncbi.nlm.nih.gov/pubmed/7892275
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