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Loss of Function of KRE5 Suppresses Temperature Sensitivity of Mutants Lacking Mitochondrial Anionic Lipids

Disruption of PGS1, which encodes the enzyme that catalyzes the committed step of cardiolipin (CL) synthesis, results in loss of the mitochondrial anionic phospholipids phosphatidylglycerol (PG) and CL. The pgs1Δ mutant exhibits severe growth defects at 37°C. To understand the essential functions of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhong, Quan, Gvozdenovic-Jeremic, Jelena, Webster, Paul, Zhou, Jingming, Greenberg, Miriam L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC545902/
https://ncbi.nlm.nih.gov/pubmed/15563612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0808
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