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Loss of Cardiolipin Leads to Longevity Defects That Are Alleviated by Alterations in Stress Response Signaling

Perturbation of cardiolipin (CL) synthesis in yeast cells leads to defective respiratory chain function and mitochondrial DNA loss, both of which have been implicated in aging in mammals. The availability of yeast CL mutants enabled us to directly investigate the role of CL synthesis in aging. In th...

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書目詳細資料
Main Authors: Zhou, Jingming, Zhong, Quan, Li, Guiling, Greenberg, Miriam L.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709391/
https://ncbi.nlm.nih.gov/pubmed/19401462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003236
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