Actin-depolymerizing Factor and Cofilin-1 Play Overlapping Roles in Promoting Rapid F-Actin Depolymerization in Mammalian Nonmuscle Cells

Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all eukaryotes. In vitro, ADF/cofilins promote actin dynamics by depolymerizing and severing actin filaments. However, whether ADF/cofilins contribute to actin dynamics in cells by disassembling “old” actin filament...

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Bibliographic Details
Main Authors: Hotulainen, Pirta, Paunola, Eija, Vartiainen, Maria K., Lappalainen, Pekka
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2005
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545901/
https://ncbi.nlm.nih.gov/pubmed/15548599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0555
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