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Xrs2p Regulates Mre11p Translocation to the Nucleus and Plays a Role in Telomere Elongation and Meiotic Recombination

The Mre11-Rad50-Xrs2 (MRX) protein complex plays pivotal roles in meiotic recombination, repair of damaged DNA, telomere elongation, and cell cycle checkpoint control. Xrs2p is known to be essential for all the functions of the complex, but its role in the complex has not been clearly elucidated. A...

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Bibliographic Details
Main Authors: Tsukamoto, Yasumasa, Mitsuoka, Chikako, Terasawa, Masahiro, Ogawa, Hideyuki, Ogawa, Tomoko
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545897/
https://ncbi.nlm.nih.gov/pubmed/15548595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0782
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