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The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast.

The Mre11p/Rad50p/Xrs2p complex is involved in the repair of double-strand DNA breaks, nonhomologous end joining, and telomere length regulation. TEL1 is primarily involved in telomere length regulation. By an epistasis analysis, we conclude that Tel1p and the Mre11p/Rad50p/Xrs2p complex function in...

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Bibliografski detalji
Glavni autori: Ritchie, K B, Petes, T D
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1461057/
https://ncbi.nlm.nih.gov/pubmed/10790418
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