The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

A subset of long noncoding RNAs (lncRNAs) is spatially correlated with transcription factors (TFs) across the genome, but how these lncRNA–TF gene duplexes regulate tissue development and homeostasis is unclear. We identified a feedback loop within the NANCI (Nkx2.1-associated noncoding intergenic R...

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Vydáno v:Genes Dev
Hlavní autoři: Herriges, Michael J., Tischfield, David J., Cui, Zheng, Morley, Michael P., Han, Yumiao, Babu, Apoorva, Li, Su, Lu, MinMin, Cendan, Isis, Garcia, Benjamin A., Anderson, Stewart A., Morrisey, Edward E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458756/
https://ncbi.nlm.nih.gov/pubmed/28546511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.298018.117
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