The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

A subset of long noncoding RNAs (lncRNAs) is spatially correlated with transcription factors (TFs) across the genome, but how these lncRNA–TF gene duplexes regulate tissue development and homeostasis is unclear. We identified a feedback loop within the NANCI (Nkx2.1-associated noncoding intergenic R...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Herriges, Michael J., Tischfield, David J., Cui, Zheng, Morley, Michael P., Han, Yumiao, Babu, Apoorva, Li, Su, Lu, MinMin, Cendan, Isis, Garcia, Benjamin A., Anderson, Stewart A., Morrisey, Edward E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458756/
https://ncbi.nlm.nih.gov/pubmed/28546511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.298018.117
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