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HSV-1 ICP27 induces apoptosis by promoting Bax translocation to mitochondria through interacting with 14-3-3θ

The subcellular localization of Bax plays a crucial role during apoptosis. In response to apoptotic stimuli, Bax translocates from the cytoplasm to the mitochondria, where it promotes the release of cytochrome c to the cytoplasm. In cells infected with HSV-1, apoptosis is triggered or blocked by div...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Kim, Ji Ae, Kim, Jin Chul, Min, Jung Sun, Kang, Inho, Oh, Jeongho, Ahn, Jeong Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458675/
https://ncbi.nlm.nih.gov/pubmed/28256197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.5.023
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