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The N-terminal to C-terminal motif in protein folding and function

Essentially all proteins known to fold kinetically in a two-state manner have their N- and C-terminal secondary structural elements in contact, and the terminal elements often dock as part of the experimentally measurable initial folding step. Conversely, all N–C no-contact proteins studied so far f...

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Autori principali: Krishna, Mallela M. G., Englander, S. Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC545867/
https://ncbi.nlm.nih.gov/pubmed/15657118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409114102
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