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The N-terminal to C-terminal motif in protein folding and function

Essentially all proteins known to fold kinetically in a two-state manner have their N- and C-terminal secondary structural elements in contact, and the terminal elements often dock as part of the experimentally measurable initial folding step. Conversely, all N–C no-contact proteins studied so far f...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Krishna, Mallela M. G., Englander, S. Walter
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409114102
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