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Design of live attenuated bacterial vaccines based on D-glutamate auxotrophy
Vaccine development is a priority for global health due to the growing multidrug resistance in bacteria. D-glutamate synthesis is essential for bacterial cell wall formation. Here we present a strategy for generating effective bacterial whole-cell vaccines auxotrophic for D-glutamate. We apply this...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458566/ https://ncbi.nlm.nih.gov/pubmed/28548079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15480 |
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