Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

Falciparum malaria is initiated when Anopheles mosquitoes transmit the Plasmodium sporozoite stage during a blood meal. Irradiated sporozoites confer sterile protection against subsequent malaria infection in animal models and humans. This level of protection is unmatched by current recombinant mala...

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Detalhes bibliográficos
Main Authors: VanBuskirk, Kelley M., O'Neill, Matthew T., De La Vega, Patricia, Maier, Alexander G., Krzych, Urszula, Williams, Jack, Dowler, Megan G., Sacci, John B., Kangwanrangsan, Niwat, Tsuboi, Takafumi, Kneteman, Norman M., Heppner, Donald G., Murdock, Brant A., Mikolajczak, Sebastian A., Aly, Ahmed S. I., Cowman, Alan F., Kappe, Stefan H. I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714279/
https://ncbi.nlm.nih.gov/pubmed/19625622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906387106
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