Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design

Falciparum malaria is initiated when Anopheles mosquitoes transmit the Plasmodium sporozoite stage during a blood meal. Irradiated sporozoites confer sterile protection against subsequent malaria infection in animal models and humans. This level of protection is unmatched by current recombinant mala...

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Main Authors: VanBuskirk, Kelley M., O'Neill, Matthew T., De La Vega, Patricia, Maier, Alexander G., Krzych, Urszula, Williams, Jack, Dowler, Megan G., Sacci, John B., Kangwanrangsan, Niwat, Tsuboi, Takafumi, Kneteman, Norman M., Heppner, Donald G., Murdock, Brant A., Mikolajczak, Sebastian A., Aly, Ahmed S. I., Cowman, Alan F., Kappe, Stefan H. I.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714279/
https://ncbi.nlm.nih.gov/pubmed/19625622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906387106
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