The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition

Adenocarcinoma (ADC) and squamous cell carcinoma (SqCC) are the two predominant subtypes of non-small cell lung cancer (NSCLC) and are distinct in their histological, molecular and clinical presentation. However, metabolic signatures specific to individual NSCLC subtypes remain unknown. Here, we per...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Goodwin, Justin, Neugent, Michael L., Lee, Shin Yup, Choe, Joshua H., Choi, Hyunsung, Jenkins, Dana M. R., Ruthenborg, Robin J., Robinson, Maddox W., Jeong, Ji Yun, Wake, Masaki, Abe, Hajime, Takeda, Norihiko, Endo, Hiroko, Inoue, Masahiro, Xuan, Zhenyu, Yoo, Hyuntae, Chen, Min, Ahn, Jung-Mo, Minna, John D., Helke, Kristi L., Singh, Pankaj K., Shackelford, David B., Kim, Jung-whan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458561/
https://ncbi.nlm.nih.gov/pubmed/28548087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15503
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi