Expanding glycosaminoglycan chemical space: towards the creation of sulfated analogs, novel polymers and chimeric constructs

Glycosaminoglycans (GAGs) have therapeutic potential in areas ranging from angiogenesis, inflammation, hemostasis and cancer. GAG bioactivity is conferred by intrinsic structural features, such as disaccharide composition, glycosidic linkages and sulfation pattern. Unfortunately, the in vitro enzyma...

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Bibliografski detalji
Izdano u:Glycobiology
Glavni autori: Lane, Rachel S, St. Ange, Kalib, Zolghadr, Behnam, Liu, Xinyue, Schäffer, Christina, Linhardt, Robert J, DeAngelis, Paul L
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Original articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458544/
https://ncbi.nlm.nih.gov/pubmed/28334971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx021
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