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Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
RNAi is a conserved mechanism in which small RNAs induce silencing of complementary targets. How Argonaute-bound small RNAs are targeted for degradation is not well understood. We show that the adenyl-transferase Cid14, a member of the TRAMP complex, and the uridyl-transferase Cid16 add non-template...
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| Publicado en: | Nat Commun |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458512/ https://ncbi.nlm.nih.gov/pubmed/28541282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15332 |
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