Imaging bacterial infections with radiolabeled 1-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-5-iodouracil

Bacterial infections provide diagnostic dilemmas that could be enlightened by modern imaging technologies. We have developed a simple method for imaging bacterial infections in mice that relies on the phosphorylation and trapping of the thymidine kinase (TK) substrate 1-(2′-deoxy-2′-fluoro-β-d-arabi...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Bettegowda, Chetan, Foss, Catherine A., Cheong, Ian, Wang, Yuchuan, Diaz, Luis, Agrawal, Nishant, Fox, James, Dick, James, Dang, Long H., Zhou, Shibin, Kinzler, Kenneth W., Vogelstein, Bert, Pomper, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15653773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408861102
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