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Herpes Simplex Virus Thymidine Kinase Imaging in Mice with (1-(2’-deoxy-2’-[(18)F] fluoro-1-β-D-arabinofuranosyl)-5-iodouracil) and metabolite (1-(2’-deoxy-2’-[(18)F] fluoro-1-β-D-arabinofuranosyl)-5-uracil)

FIAU, (1-(2’-deoxy-2’-fluoro-1-β-D-arabinofuranosyl)-5-iodouracil) has been used as a substrate for herpes simplex virus thymidine kinases (HSV-TK and HSV-tk, for protein and gene expression respectively) and other bacterial and viral thymidine kinases for noninvasive imaging applications. Previous...

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Bibliografiske detaljer
Main Authors: Nimmagadda, S, Mangner, TJ, Lawhorn-Crews, JM, Haberkorn, U, Shields, AF
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107601/
https://ncbi.nlm.nih.gov/pubmed/19506865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-009-1177-y
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