IGFBP2 Produces Rapid-Acting and Long-Lasting Effects in Rat Models of Posttraumatic Stress Disorder via a Novel Mechanism Associated with Structural Plasticity

BACKGROUND: Posttraumatic stress disorder is an anxiety disorder characterized by deficits in the extinction of aversive memories. Insulin-like growth factor 1 (IGF1) is the only growth factor that has shown anxiolytic and antidepressant properties in human clinical trials. In animal studies, insuli...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Burgdorf, Jeffrey, Colechio, Elizabeth M., Ghoreishi-Haack, Nayereh, Gross, Amanda L., Rex, Christopher S., Zhang, Xiao-lei, Stanton, Patric K., Kroes, Roger A., Moskal, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Regular Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458343/
https://ncbi.nlm.nih.gov/pubmed/28158790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx007
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