Insulin-Like Growth Factor I Produces an Antidepressant-Like Effect and Elicits N-Methyl-D-Aspartate Receptor Independent Long-Term Potentiation of Synaptic Transmission in Medial Prefrontal Cortex and Hippocampus

BACKGROUND: Growth factors play an important role in regulating neurogenesis and synapse formation and may be involved in regulating the antidepressant response to conventional antidepressants. To date, Insulin-like growth factor I (IGFI) is the only growth factor that has shown antidepressant prope...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Burgdorf, Jeffrey, Zhang, Xiao-lei, Colechio, Elizabeth M., Ghoreishi-Haack, Nayereh, Gross, Amanda, Kroes, Roger A., Stanton, Patric K., Moskal, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772825/
https://ncbi.nlm.nih.gov/pubmed/26374350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv101
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