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Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades

Dopamine- and cAMP-regulated phosphoprotein of 32 kDa (DARPP-32) plays a central role in medium spiny neurons in the neostriatum in the integration of various neurotransmitter signaling pathways. In its Thr-34-phosphorylated form, it acts as a potent protein phosphatase-1 inhibitor, and, in its Thr-...

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Bibliografiska uppgifter
Huvudupphovsmän: Nishi, Akinori, Watanabe, Yasuo, Higashi, Hideho, Tanaka, Masatoshi, Nairn, Angus C., Greengard, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC545831/
https://ncbi.nlm.nih.gov/pubmed/15657149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409138102
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